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Showing posts with label IGOR CHUDOV. Show all posts
Showing posts with label IGOR CHUDOV. Show all posts

Thursday, February 08, 2024

COVID Vaccines Are Most Dangerous in the First Trimester of Pregnancy, Study Suggests

Swedish and Norwegian newborns: postnatal outcomes depend on vaccination trimester IGOR CHUDOV FEB 8 A new study was published in JAMA yesterday. https://jamanetwork.com/journals/jama/fullarticle/2814537 Its objective was to prove that COVID vaccines are “safe for pregnancy.” Meaning In this large population-based study, vaccination of pregnant individuals with mRNA COVID-19 vaccines was not associated with increased risks of neonatal adverse events in their infants. Indeed, authors show that infants born to vaccinated mothers experience fewer adverse outcomes compared to unvaccinated mothers: Results Of 196 470 newborn infants included (51.3% male, 93.8% born at term, 62.5% born in Sweden), 94 303 (48.0%) were exposed to COVID-19 vaccination during pregnancy. Exposed infants exhibited no increased odds of adverse neonatal outcomes, and they exhibited lower odds for neonatal nontraumatic intracranial hemorrhage (event rate, 1.7 vs 3.2/1000; adjusted odds ratio [aOR], 0.78 [95% CI, 0.61-0.99]), hypoxic-ischemic encephalopathy (1.8 vs 2.7/1000; aOR, 0.73 [95% CI, 0.55-0.96]), and neonatal mortality (0.9 vs 1.8/1000; aOR, 0.68 [95% CI, 0.50-0.91]). The authors admit: It is unlikely that mRNA COVID-19 vaccination during pregnancy directly reduces neonatal mortality, although others have suggested that such a protective effect is biologically plausible.12 The vaccine does not seem to pass the placenta or induce placental inflammation, and could not be traced in cord blood.25,26 The current study’s results could not elucidate the mechanisms that explain why infants of vaccinated individuals had lower risks of some outcomes including mortality. Unmeasured confounding due to vaccinated individuals being healthier may have contributed to the lower neonatal morbidity and mortality associated with COVID-19 vaccination during pregnancy. I will show that the data provided in the study, including subgroup and trimester analysis, suggests that Covid vaccines given to pregnant women may be dangerous to fetuses if the mothers were vaccinated during the first trimester. Let’s look. Sensitivity and Trimester Analyses This study of infants born in Sweden and Norway during the pandemic includes valuable and hard-to-find data: Sensitivity analyses show subsets of mothers, for example, vaccinated mothers who did not have COVID-19 during pregnancy. Breakdown by the trimester of COVID vaccine exposure. When looked at together, the data mentioned above raises serious questions about Covid vaccine safety in pregnancy. Those who tout the benefits of maternal COVID vaccination often state that vaccines prevent COVID-19, which is dangerous to fetuses. This study has a sensitivity analysis that belies this theory. First of all, COVID vaccines did NOT meaningfully reduce infections during pregnancy, as Table 1 shows: The sensitivity analysis data shows that the infants whose mothers avoided COVID-19 during pregnancy have similar outcomes to all infants (including the ones whose mothers had Covid during pregnancy): Therefore, “vaccine protection against infection” does not reduce the relative risk of adverse outcomes. Looking at the subset of mothers who did not have Covid shows that infections have nothing to do with the relative risk of those adverse outcomes. The authors suggest that “unexplained confounders,” sometimes described as the “healthy vaccinee effect,” may be the reason for the reduced relative risk of vaccinated vs. unvaccinated outcomes. Disturbing Difference Between First and Third Trimester Vaccinations Imagine a perfectly useless but harmless substance: a saline shot or a sugar pill. A treatment of that kind, given to pregnant mothers, would not result in disparate outcomes based on the trimester of exposure. Stating the same in scientific terms, the relative risk of adverse events experienced by newborns whose mothers were given a harmless substance would not depend on the trimester of exposure. Why, then, do newborns whose mothers were vaccinated in the first trimester of pregnancy (when major organs form) experience approximately 50% greater rates of adverse postnatal events than those born to mothers vaccinated in the third trimester? Take a look at this: Rates of almost all negative infant outcomes (circled in blue) are worse for first-trimester infants compared to third-trimester infants. Can we perform a statistical test on some of these differences to see whether the disparity in the outcomes in the two samples could arise due to pure chance? Look at the above outcome, “neonatal thrombocytopenia,” highlighted in red. The proper statistical test for this is called a “two-proportion Z-test”: The data shows that infants exposed to the vaccine earlier (in the first trimester of pregnancy) are more likely to have thrombocytopenia after birth. P = 0.00001 suggests that the difference did not occur due to chance. The only explanation that I can personally muster is that Covid vaccines, given in the first trimester, somehow interfere with fetal development and make thrombocytopenia (and a host of other outcomes) more likely to happen. The same effect appears when looking at “all adverse outcomes.” See supplement: Infants exposed in the first trimester have 0.68/0.49 - 1 = 39% greater risk of having any adverse outcome. How can a “safe vaccine” that “does not affect pregnancy” make the first trimester of exposure more dangerous? A similar finding was recently seen in another study: the risk of neurodevelopmental disorders was similarly higher for first-trimester exposure compared to third-trimester: ht tps://www.igor-chudov.com/p/male-infants-and-male-rat-pups-disproportionally Summary A sub-analysis of pregnancies that avoided COVID-19 shows that the “reduction in adverse outcomes due to vaccines” is likely due to confounding, not reduction in infections. At the same time, the unexplainable disparity between infants exposed in the first trimester and infants exposed in the third trimester suggests that the Covid vaccines negatively affect fetal development. What do you think? Is there a pattern suggesting that Covid vaccines are not safe for pregnancy? Let us know what you think - and feel free to disagree with me! Share Igor’s Newsletter. © 2024 Igor Chudov 548 Market Street PMB 72296, San Francisco, CA 94104

Saturday, January 27, 2024

Male Infants and Male Rat Pups Disproportionally Affected by mRNA COVID Vaccines Given to Pregnant Mothers

Mysterious sex difference demonstrated by two separate studies IGOR CHUDOV JAN 27 I recently described a scientific study that found that COVID-19 vaccines cause “autism-like behavior in male rats.” Igor’s Newsletter COVID Vaccines Cause Autism in Lab Rats, Study Finds A friend of this blog, Ashmedai, highlighted a fascinating animal study, which found that giving pregnant rats the Pfizer COVID vaccine induced ‘autism-like’ traits in the male pups born after such vaccination. The placebo-controlled study was published in… Read more 15 days ago · 433 likes · 336 comments · Igor Chudov A new study conducted to prove that “COVID vaccines are safe in pregnancy” coincidentally exposes a similar developmental problem, this time in male humans instead of lab rats. https://jamanetwork.com/journals/jamapediatrics/fullarticle/2814106 This study is relatively straightforward. It looked at children born to vaccinated and unvaccinated mothers during the pandemic. Scientists compared how well the children met developmental milestones at 12 and 18 months. In the chart below, the vaccine appears harmful at the 12-month milestone but shows the opposite effect at 18 months. (this is the strangest finding I have seen recently) So, the authors conclude, Findings In this cohort study including 2261 and 1940 infants aged 12 and 18 months, respectively, in utero exposure to COVID-19 vaccination was not associated with abnormal neurodevelopmental scores on the Ages and Stages Questionnaire, third edition, at 12 or 18 months of life. However, when we dig into details, bad patterns emerge. Boys are Negatively Affected Just as the autistic newborn male rat pups we talked about last week, in this study, the boys born to vaccinated mothers were also faring worse compared to the outcome for vaccinated girls. Here’s the highlighted chart comparing boys and girls. You can see two things: A statistically significant deleterious effect of Covid vaccine on boys at age 12 months Huge difference between outcomes for boys vs girls at age 18 months, showing much worse relative risk for boys: I want to ask: if the vaccine does not affect the neurodevelopment of infants, how come boys born to vaccinated mothers have much higher risks than girls? Is there an effect that we are missing? Effect of Vaccination Trimester Another sign of the effect of COVID-19 vaccines on neurodevelopment is that children whose mothers were vaccinated in the first trimester fare the worst, with less harm seen for vaccinations done in the second trimester. Lastly, there is little effect in the third trimester. Per the supplement: Such a sex-specific and trimester-specific pattern would be impossible with a “safe” treatment that did not affect fetuses! Why are children born to mothers vaccinated in the first trimester of pregnancy do so much worse than children born to mothers vaccinated in the third trimester? Why are boys faring worse than girls if the Covid vaccine “stays in the arm”? I hope that we can get further answers on this! What do you think? Why are boys affected disproportionally? Igor’s Newsletter © 2024 Igor Chudov 548 Market Street PMB 72296, San Francisco, CA 94104

Sunday, January 21, 2024

mRNA Technology Is the Culprit Behind Faulty Immune Response That Prolonged the Pandemic, IgG4 Study Shows Mistakes Were Made IGOR CHUDOV JAN 21

This blog previously covered several scientific discoveries related to the “IgG4 antibody class switch.” IgG4 refers to a special rare subclass of antibodies instructing our immune system to ignore a pathogen rather than fight it. We learned that repeat COVID vaccinations cause immune tolerance in boosted people, which makes them less able to fend off repeat infections. While IgG4 antibodies may naturally appear in allergies due to repeat immune stimulations with allergens, they are inappropriate for replicating pathogens such as Sars-Cov-2. What causes such dysfunctional antibodies to appear in COVID-boosted people? Was the IgG4 class switch mechanistically caused by repeat injections or by the nature of mRNA technology? In August of 2023, I suggested that the culprit may be continued production of spike protein encoded by the mRNA COVID vaccines. An interesting new preprint study confirms that suggestion. It compared the immune outcomes of three injections with mRNA vaccines against the effects of three injections of a protein-based vaccine called Novavax. Scientists discovered that, despite all groups of patients receiving three injections, the IgG4 class switch happened only in the mRNA group. Compared with recipients of prior mRNA vaccine, anti-S IgG3 levels were markedly higher (>10-fold) after three or four homologous doses of NVXCoV2373. By contrast, much higher anti-S IgG4 levels (>75-fold) were observed following repeated mRNA vaccination, but not after three or four homologous doses of NVX-CoV2373 (Fig. 1A). The study compared three groups of patients: Those who received three doses of the Pfizer mRNA vaccine Those who received three doses of the Moderna mRNA vaccine Those who received three doses of Novavax COVID vaccine (no mRNA) The Novavax vaccine has no mRNA and is an injection of “spike protein,” adjuvanted with a certain substance called Matrix-M. The job of the adjuvant is to make the vaccinated person feel sick and trigger an immune reaction to the protein contained in the vaccine shot. Many other vaccines given to people in the past were of this type. You can see that, compared to Novavax, mRNA vaccines result in IgG4 levels that are THOUSANDS OF TIMES greater (the scales below are logarithmic): What can we conclude from this? The Novavax group, as well as the mRNA groups, were thrice-vaccinated. And yet, only the mRNA groups had sky-high levels of IgG4 antibodies. Study authors explain: Increased concentrations of IgG4 have been associated with immunosuppression and poor clinical outcomes of COVID-19, and while generally regarded as anti-inflammatory, may contribute to some autoimmune disorders and inflammatory IgG4- related diseases. Following repeated mRNA vaccination, IgG4 was observed to increase from 0.04% of total SARS-CoV-2 spike–specific IgG after two doses to 19.27% after three doses. Thus, the authors showed that mRNA technology is the culprit. This explanation from a year ago shows why “immune tolerance” is harmful when an organism responds to a virus: Mistakes Were Made (with mRNA) mRNA technology has been around in scientific labs and startup companies for decades. Not one of its applications became an approved product before the COVID pandemic. Somehow, science funders and health authorities rushed to adopt this failed technology to protect us from a disease that they coincidentally developed and funded. We were told this technology was “safe and effective” based on rushed three-month trials. Later, we were told that “billions were vaccinated and no one died” - and we were forbidden to question the outcomes. Then, surprises started. Approximately a year after billions were vaccinated, mRNA-vaccinated people started getting infected and reinfected a lot more than the unvaccinated people! A study done on 50,000 health workers in Cleveland shows this: https://academic.oup.com/ofid/article/10/6/ofad209/7131292?login=false The study discussed today proves that the IgG4 class switch (causing this increased rate of reinfections) did not occur merely due to the number of jabs received. What mattered was what was injected: three mRNA injections caused a thousand times higher IgG4 levels than three Novavax injections. Conflicts of Interest The study, which we looked at today, was funded by Novavax. Hence, a standard dose of skepticism is warranted. However, its findings confirm what we have discussed many times: the mRNA vaccines create a broken immune response, which fueled the pandemic and made it worse rather than better. I am not a shill for Novavax, and I would never take a Covid vaccine of any kind, including Novavax. The objective of my post, instead, is to highlight the insanity and irreversibility of recklessly priming billions of people with an unproven novel tolerance-inducing genetic treatment. I wish they studied this effect before forcing billions of unwilling people to become subjects of a poorly considered planetary-scale science project. What do you think? Igor’s Newsletter © 2024 Igor Chudov 548 Market Street PMB 72296, San Francisco, CA 94104

Saturday, January 06, 2024

mRNA Covid Vaccines Worsen Diabetes, Study Finds Sadly, Covid does the same thing IGOR CHUDOV JAN 6

 A new study by Zhai et al. found disturbing effects of mRNA COVID vaccines on people who are diabetic or prediabetic.

Authors report that “61.1% of patients with type 2 diabetes, but not healthy controls, exhibited aggravated insulin resistance towards the booster shots of the COVID-19 vaccine”.

The study authors recruited 155 people and compared their condition before and after the mRNA COVID booster shots:

Between 1 June 2023 and 31 October 2023, we recruited 155 adults who have received two doses of the mRNA 80 COVID-19 vaccine (BNT162b2). The participants ranged in age from 18 to 65 years (median=53.5 years, IQR 12.0) and 60.25% are male. Human volunteers were recruited to determine their immune responses and glucose control before and 2 weeks after the booster.

About 61.1% of diabetic subjects had impairment of insulin sensitivity according to the HOMA-IR index and about 66.7% of diabetic subjects had increased risks of cardiovascular complications according to the TyG index.

Spike Protein is the Culprit!

I would like to compliment the authors, who bravely showed the deleterious effect of COVID-19 vaccines - something for which their careers will probably suffer - and also found out what exactly is the culprit in the COVID-19 vaccine.

It turns out to be “spike protein,” effects of which I underlined in blue, whereas conclusions about diabetes are underlined in red: